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[目的]研究多烯鱼油对大鼠血脂水平的影响。[方法]将雄性大鼠按血清总胆固醇(TC)水平随机分为对照组、低、中、高剂量组,喂饲高脂饲料,同时给与不同剂量的多烯鱼油灌胃45 d,结束时测TC、甘油三脂(TG)、高密度脂蛋白胆固醇(HDL-C)水平。[结果]多烯鱼油0.333 g/kg.BW和1.00 g/kg.BW剂量组可使大鼠血清TC、TG值降低,差异有统计学意义(P<0.05)。[结论]多烯鱼油具有降血脂的作用。
[Objective] The research aimed to study the effect of polyene fish oil on serum lipids in rats. [Methods] Male rats were randomly divided into control group, low, medium and high dose groups according to the level of serum total cholesterol (TC), fed with high-fat diet and fed with different doses of polyene fish oil for 45 days, TC, triglyceride (TG), high-density lipoprotein cholesterol (HDL-C) levels were measured. [Result] The levels of TC and TG in serum of polyene fish oil of 0.333 g / kg.BW and 1.00 g / kg.BW were decreased significantly (P <0.05). [Conclusion] Polya fish oil has the effect of lowering blood fat.