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重症肝炎仍无持殊治疗药物,欧美各国已开始以肝脏移植作治疗。现行的治疗方法是,阻止肝坏死,促进肝再生,排除中毒物质,补充缺乏物质及预防合并症等。目前,类固醇疗法,胰高糖素-胰岛素(G-I)疗法及特制氰基酸制剂是重症肝炎的主要疗法。类固醇药物通过免疫抑制作用防止新的肝细胞坏死。急性重症乙型肝炎,是由于 T 细胞破坏病毒感染的肝细胞,继而所引起的肝局部性 Arthus 反应(一种局部过敏反应),一旦引起 Arthus 反应时,类固醇药物就失去了免疫抑制剂的效果。因此,类固醇药物给予的时机,应尽早使用。给予强的松龙剂量应在60mg/d 以下。尽量短期用药。当丧失意识时,可静
Severe hepatitis is still no special treatment drugs, Europe and the United States have begun to liver transplantation for treatment. The current treatment is to prevent liver necrosis, promote liver regeneration, eliminate toxic substances, lack of substances to supplement and prevent comorbidities. Currently, steroid therapy, glucagon-insulin (G-I) therapy, and specialty cyano acid preparations are the leading treatments for severe hepatitis. Steroid drugs prevent new liver cell necrosis by immunosuppression. Acute severe hepatitis B is caused by T cells that destroy virus-infected hepatocytes and subsequently cause a local Arthus reaction (a local allergic reaction) that loses the effect of an immunosuppressant once the Arthus reaction is triggered . Therefore, the timing of steroid drug administration should be used as soon as possible. Give prednisolone dose should be below 60mg / d. Try to short-term medication. When the loss of consciousness, can be static