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目的探讨间接测量法与公式计算法指导营养支持对慢性阻塞性肺疾病(COPD)机械通气患者预后的影响。方法收集住院治疗的COPD机械通气患者64例,随机分两组,观察组采用间接测量法指导营养支持,对照组采用公式计算法指导营养支持,对比分析两种不同的计算方法对COPD机械通气患者病死率、脱机时间、呼吸机相关肺炎(VAP)发生率等预后的影响。结果对照组与观察组的病死率(9.4%vs6.2%),脱机时间[(14.6±2.4)d vs(15.4±3.1)d]及VAP发生率(21.9%vs 18.8%)方面无明显差异(P均>0.05)。结论间接测量法与公式计算法指导营养支持对COPD机械通气患者预后的影响无明显差异,但间接测量法操作简单,费用较低。
Objective To explore the influence of indirect measurement and formula calculation on the prognosis of chronic obstructive pulmonary disease (COPD) patients undergoing mechanical ventilation. Methods Sixty-four COPD patients were randomly divided into two groups. Indirect measurement was used to guide the nutritional support in the observation group. Nutritional support was instructed by the formula calculation method in the control group. Two different calculation methods were compared between the COPD patients with mechanical ventilation Mortality, off-time, ventilator-associated pneumonia (VAP) incidence and other prognosis. Results There was no significant difference between the control group and the observation group in mortality (9.4% vs 6.2%), offline time (14.6 ± 2.4d vs 15.4 ± 3.1d and VAP incidence (21.9% vs 18.8% Difference (all P> 0.05). Conclusion There is no significant difference between the indirect measurement method and the formula calculation method in guiding the nutritional support on the prognosis of COPD patients. However, the indirect measurement method is simple in operation and low in cost.