核酸杂交技术极大地推动了病毒分子生物学的进展。该技术通常包括核酸分离、提钝、膜转移、杂交等过程。目前避开核酸分离,提纯过程的方法已有多种。有人报道利用碘化钠破坏DNA和RNA后再将其结合于硪酸纤维素膜;最近也报道了几种 Nucleic acid hybridization technology has greatly promoted the progress of virus molecular biology. The technology usually includes nucleic acid isolation, blunting, membrane transfer, hybridization and other processes. At present, there are many ways to avoid the nucleic acid separation and purification process. It has been reported that the use of sodium iodide to destroy DNA and RNA and then bind to the cellulose acetate film; recently reported several