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手术阻断豚鼠内淋巴管(囊)造成了十三耳内淋巴积水。经火棉胶包埋切片、耳蜗电图、眼震电图技术进行观察。病理改变主要是耳蜗内淋巴积水,以顶回多见;前庭膜扩张增厚甚至破裂;柯替氏器、皿管纹和螺旋神经节部分变性发生较晚。球囊扩张常见。椭圆囊半规管扩张罕见且其感觉成分光镜下未见明显异常。听力损失早期以低频为主晚可累及全频。可见耳蜗重振和听阈波动现象。-SP/CAP仅少数动物术前后有统计意义的增高。半规管功能改变表现为眼震阈值提高;前庭重振;半规管轻瘫和优势偏向。积水程度与听力损失程度、半规管功能损害程度间无显著相关。
Surgery to block guinea pig lymphatic vessels (sac) caused thirteen ear lymphatic hydrops. After the fire cotton embedding section, cochlear electrogram, ocular electrogram technology to observe. Pathological changes mainly in the cochlear lymphatic hydrops to more common top; vestibular membrane expansion and thickening or even rupture; Kuttia, Pancreaticodular and spiral ganglion partial degeneration occurred later. Balloon dilatation common. Ellipsoidal capsule semicircular canal expansion rare and its sensory component light microscope no significant abnormalities. Earlier hearing loss mainly affects the full range of low frequency. Visible cochlear vibration and threshold fluctuations. -SP / CAP only a small number of animals before and after surgery statistically significant increase. Changes in semicircular canal function showed increased nystagmus threshold; vestibular revival; semicircular canal paresis and superiority bias. The degree of hydrocephalus and hearing loss, semicircular canal dysfunction no significant correlation between.