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肺癌是发生率及死亡率最高的恶性肿瘤之一[1],而肺叶切除是能够耐受手术的早期非小细胞肺癌(nonsmall cell lung cancer,NSCLC)患者治疗的金标准[2]。然而部分早期NSCLC患者因高龄、心肺功能储备不足或可能存在的手术并发症未能进行手术治疗[3]。立体定向放疗(stereotactic ablative radiotherapy,SABR)利用计算机技术,在三维方向上与肿瘤靶区高度一致,在肿瘤靶区受到高剂量照射的同时最大限度地保护周围正常组织。与传统放疗相比,SABR能够延长患者生存,并减少放疗并发症的发生率[4]。但是
Lung cancer is one of the most commonly occurring malignancies [1], and lobectomy is the gold standard for the treatment of patients with early-stage nonsmall cell lung cancer (NSCLC) that is resistant to surgery [2]. However, some patients with early-stage NSCLC may not be surgically treated for advanced age, inadequate cardiopulmonary reserve or possible surgical complications [3]. Stereotactic radiotherapy (stereotactic ablative radiotherapy, SABR) using computer technology, in the three-dimensional direction with the tumor target area height, the tumor target area by high doses of radiation at the same time to maximize the protection of surrounding normal tissue. Compared with traditional radiotherapy, SABR can prolong the survival of patients and reduce the incidence of radiotherapy complications [4]. but