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目的评价经皮椎体成形术(PVP)配合中药治疗骨质疏松性椎体压缩性骨折的临床疗效。方法将2013年3月至2015年3月96例骨质疏松性压缩性骨折患者随机分为观察组和对照组,每组48例。观察组采用PVP手术配合中药治疗,对照组采用保守方法治疗。随访观察患者术前,术后3 d、1个月疼痛视觉模拟评分(VAS)、Oswestry功能评分。结果观察组:VAS评分由术前(8.5±2.1)分改善到术后3 d(2.5±1.6)分,术后1个月(2.6±1.5)分;Oswestry评分由术前(42.5±9.6)分改善到术后3 d(20.5±9.6)分,术后1个月(22.5±9.6)分;VAS评分、Oswestry功能评分术前与术后3 d比较差异有统计学意义(P<0.05),术前与术后1个月比较差异有统计学意义(P<0.05)。术后3 d与术后1个月比较差异未见统计学意义(P>0.05)。各项观察项目中,观察组均优于对照组,差异均有统计学意义(P<0.05)。结论经皮椎体成形术配合中药治疗骨质疏松性椎体压缩性骨折疗效显著,能在短期内明显缓解疼痛症状,减少腰背部功能障碍,提高生活质量,是一种安全、有效的治疗方法。
Objective To evaluate the clinical efficacy of percutaneous vertebroplasty (PVP) combined with traditional Chinese medicine in the treatment of osteoporotic vertebral compression fractures. Methods From March 2013 to March 2015, 96 patients with osteoporotic compression fracture were randomly divided into observation group and control group, 48 cases in each group. The observation group was treated with PVP with traditional Chinese medicine and the control group with conservative treatment. The patients were followed up for visual analogue scale (VAS) and Oswestry function score before operation, 3 days and 1 month after operation. Results In the observation group, the VAS score improved from 8.5 ± 2.1 before surgery to 2.5 ± 1.6 after surgery and 2.6 ± 1.5 months after surgery. The Oswestry score improved from 42.5 ± 9.6 before surgery, (20.5 ± 9.6) and 1 month (22.5 ± 9.6) postoperatively respectively. There was significant difference between VAS score and Oswestry functional score before and after 3 days (P0.05) There was significant difference between preoperative and postoperative one month (P <0.05). No significant difference was found between 3 days and 1 month after surgery (P> 0.05). Among the observation items, the observation group was superior to the control group, the differences were statistically significant (P <0.05). Conclusion Percutaneous vertebroplasty combined with traditional Chinese medicine treatment of osteoporotic vertebral compression fractures significant effect, can significantly relieve pain symptoms in the short term, reduce dysfunction of the lower back and improve the quality of life, is a safe and effective treatment .