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为了前瞻性研究局部动脉内溶栓治疗急性脑梗死的疗效，应用超导技术对３７例急性脑梗死病人临近梗死部位的脑血管内注入溶栓药物治疗。其中２２例使用蝮蛇抗栓酶３号，１５例使用尿激酶溶栓。结果：２７．０３％的患者在６小时内溶栓，２４．３２％在７～１２小时内，２１．６３％在１３～２４小时内，２４．３２％在２５～４８小时内，２．７％在４８小时以后溶栓。溶栓后症状明显好转者占５９．５％，好转者２１．６％，无改善１８．９％，其中２例于溶栓后９天及１个月死亡。两种药物组疗效差异无统计学意义。术后血管再通及侧支循环开放率为７４．３％。结论：早期局部血管内溶栓治疗对脑梗死疗效显著。
In order to prospectively study the efficacy of local intra-arterial thrombolysis in the treatment of acute cerebral infarction, thrombolytic drugs were injected into the cerebral blood vessels of 37 patients with acute cerebral infarction near the infarct site by using superconducting technique. Of which 22 cases of viper antithrombin 3, 15 cases of urokinase thrombolysis. Results: 27.03% patients within 6 hours thrombolysis, 24.32% in 7 to 12 hours, 21.63% in 13 to 24 hours, 24.32% in 25 to 48 hours, 2. Thrombolysis occurred in 7% at 48 hours. Fifty-five (59.5%) patients had symptoms improvement after thrombolysis, 21.6% improvement (18.9%) did not improve, and two of them died at 9 days and one month after thrombolysis. There was no significant difference between the two drug groups. Postoperative recanalization and collateral circulation rate was 74.3%. Conclusion: Early local endovascular thrombolysis has a significant effect on cerebral infarction.