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作者对40例肾功衰竭病人高剂量尿路造影前后的肾功作了回顾性研究,无一例在造影后出现过少尿性急性肾衰。37例未因造影而使肾衰加重,3例在造影后一周内血清肝酸酐有过暂时性升高,但无尿少。近年来美国文献中有关尿路造影后(包括高剂量造影)出现急性肾衰的报告激增。因此,作者同北美在有关尿路造影后造影剂肾毒性方面的经验,有着很大差别。为了解释这种差别,复习了文献,寻找病人之间或造影技术之间的不同点。作者病例中糖尿病人数少(4例中仅有2例),而北美报告的163例造影后的急性肾衰者中有79例
The author retrospectively studied the renal function of 40 patients with renal failure before and after high-dose urography. None of them had oliguric acute renal failure after radiography. 37 cases did not make renal failure due to angiography, 3 cases in the week after angiography serum had a temporary increase in hepatic anhydride, but no less urine. In recent years there has been a surge in reports in the U.S. literature about acute renal failure after urography (including high-dose contrast). Therefore, there is a big difference between the author and North American experience in contrast nephrotoxicity after urography. To explain this difference, the literature was reviewed to find differences between patients or between radiographic techniques. The authors reported a small number of patients with diabetes (only 2 of 4), while 79 of the 163 patients with acute renal failure after angiography reported in North America