[目的]总结O139霍乱疫情应对经验,为今后的霍乱防治和处置提供借鉴。[方法]对2009年1月在玉溪市所属通海县四街镇四寨村发生一起霍乱暴发疫情,从病例的发现、确诊、报告、现场调查与处理、技术应对与行政应对等方面进行分析。[结果]在所有参宴的639人中,通过粪便或肛拭子检验,结合临床症状,确诊O139型霍乱病例20例(其中实验室确诊17例,临床诊断3例),罹患率为3.13%;检出O139型霍乱弧菌健康带菌者27人,带菌率为4.23%。未发生二代病例、无死亡病例,疫情在1周内完全控制。检测霍乱病例和带菌者的密切接触者228人,检测当地未参加丧宴的67例腹泻病例标本,检测暴发点外环境标本432份,均未检出霍乱弧菌。条件Logistics回归分析结果,丧宴提供的煮萝卜是发病/带菌的危险因素,OR值为3.71。[结论]这是一起由O139霍乱弧菌引起的输入性食源性霍乱暴发疫情,由于发现、诊断、报告及时,应急处置措施得当,疫情得到快速彻底控制。 [Objective] To summarize the experience of response to cholera outbreak in O139 and provide reference for the prevention and treatment of cholera in the future. [Method] An outbreak of cholera outbreak was reported in January 2009 in Sihai Village, Sijie Town, Tonghai County, Yuxi City from the discovery, diagnosis, report, field investigation and treatment of cases, technical response and administrative response. [Results] Among all the 639 participants, 20 cases of type O 139 cholera were confirmed by fecal or anal swab test combined with clinical symptoms (of which 17 were laboratory confirmed and 3 were clinically diagnosed), and the attack rate was 3.13% ; 27 healthy carriers of Vibrio cholerae O139 were detected with a rate of 4.23%. The second generation of cases did not occur, no deaths, the outbreak within 1 week of complete control. 228 cholera cases and close contacts of carriers were detected. 67 cases of diarrhea cases that did not attend the funeral dinner were detected, and 432 cases of environmental samples outside the outbreak were detected. Vibrio cholerae was not detected. Conditioned logistic regression analysis showed that boiled radish provided the risk factor for onset / carriage, with an odds ratio of 3.71. [Conclusion] This is an outbreak of imported foodborne cholera caused by Vibrio cholerae O139. The epidemic was quickly and completely controlled because of proper diagnosis, timely reporting and emergency response measures.