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目的：探讨女性生殖系统非霍奇金淋巴瘤（NHL）的发病、诊断及治疗。方法：临床资料回顾性分析。结果：11例生殖系统非霍奇金淋巴瘤NHL中，发生于外阴1例、宫颈3例、宫体2例、卵巢5例。以宫颈与卵巢受累为主，占72．7％（8／11）。7例为原发，4例为继发。8例采用以根治性手术为主，辅以CHOP（COP）方案化疗的综合治疗方法，完全缓解6例，占75．0％。生存期最长已超过10年零8个月。结论：女性生殖系统非霍奇金淋巴瘤（NHL） 有原发和继发。肿瘤标记物、细胞学检查、病理组织学及免疫组化技术均可作为诊断与鉴别诊断的手段。根治性手术＋CHOP方案化疗的综合治疗方法可达根治目的。
Objective: To investigate the incidence, diagnosis and treatment of female non-Hodgkin’s lymphoma (NHL) in the reproductive system. Methods: Retrospective analysis of clinical data. RESULTS: Of the 11 cases of non-Hodgkin’s lymphoma in the reproductive system, NHL occurred in 1 case of vulva, 3 cases of cervix, 2 cases of uterine cavity, and 5 cases of ovary. The main cervix and ovary involvement accounted for 72.7% (8/11). 7 cases were primary and 4 cases were secondary. Eight patients were treated with radical surgery and supplemented with CHOP (COP) chemotherapy. Complete remission was achieved in 6 patients, accounting for 75.0%. The longest survival period has exceeded 10 years and 8 months. Conclusions: Female reproductive system non-Hodgkin lymphoma (NHL) has primary and secondary. Tumor markers, cytology, histopathology, and immunohistochemistry can all be used as diagnostic and differential diagnostic tools. The combined treatment of radical surgery + CHOP chemotherapy can achieve the goal of radical cure.