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晚近,由于细胞染色方法的改进,电子显微镜的应用,细胞免疫荧光技术的进展,放射免疫法(RIA)激素微量测定的成功,显微外科技术的发展,因而对垂体腺瘤的研究有了不少突破。本文对其分类、早期诊断及手术方法的进展作简单介绍。 一、有关垂体腺瘤的分类 多年来,垂体腺瘤的常规分类,是根据光学显微镜和用苏木精—伊红或三色染色,附加PAS和橘黄G染色所证实的主要细胞类型而定。依据其形态学分为嫌色、嗜酸、嗜碱、混合等四型。偶尔亦有其他类型的恶性腺瘤。过去垂体腺瘤中占有很大比例的无分泌作用的“嫌色”腺瘤,晚近由于组织化学染色的应
Recently, studies on pituitary adenomas have been made due to improvements in cell staining methods, application of electron microscopes, progress of cellular immunofluorescence techniques, success of microarray determination of radioimmunoassay (RIA) hormones, and development of microsurgical techniques Breakthrough. This article gives a brief introduction of its classification, early diagnosis and progress of surgical methods. 1. Classification of Pituitary Adenomas The general classification of pituitary adenomas has been based on optical microscopy and identification of the major cell types confirmed by hematoxylin-eosin or trichrome, PAS and orange G staining over the years. According to their morphology is divided into color, acidophilic, basophilic, mixed and other four types. Occasionally there are other types of malignant adenomas. Pituitary adenomas in the past occupy a large proportion of non-secretion of “chromophobe” adenomas, due to the recent histochemical staining should