乳腺癌是女性高发的恶性肿瘤,其发病率呈逐年上升趋势。尽管临床研究已经取得了较大的进步,但是其复发及转移率仍然很高。乳腺癌的预后与其恶性程度、转移与否、血管生成状况、治疗措施等密切相关。有意义的预后或预测性的标志物的使用对临床医师来说在鉴别复发的危险性和针对 Breast cancer is a high incidence of malignant tumors in women, the incidence showed a rising trend year by year. Although clinical research has made great progress, its recurrence and metastasis rates are still high. The prognosis of breast cancer and its malignancy, metastasis or not, angiogenesis, treatment measures are closely related. The use of meaningful prognostic or predictive markers is of great importance to clinicians in identifying the risk of relapse and