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本文报告64例经手术和病理证实的15岁以下儿童后颅窝神经胶质细胞瘤,其中学龄期儿童占65.63%;肿瘤的组织学类型以星形细胞瘤为最多,占35.94%,其次为髓母细胞瘤、室管膜瘤;近一半肿瘤发生于小脑蚓部,颅内压增高为其主要临床特征。作者分析了本组病例延误诊治的可能因素,强调早期诊断、早期手术治疗及术后辅以放疗、化疗等综合措施对提高疗效延长生存期的重要性。
This article reports 64 cases of posterior fossa glioma tumor confirmed by surgery and pathology in children under 15 years of age, of which 65.63% of children of school age; histological types of tumors to astrocytoma up to 35.94 %, Followed by medulloblastoma, ependymoma; nearly half of tumors occurred in the cerebellar vermis, increased intracranial pressure is its main clinical features. The authors analyzed the possible causes of delayed diagnosis and treatment in this group of patients and emphasized the importance of early diagnosis, early surgical treatment and postoperative radiotherapy and chemotherapy combined measures to improve the efficacy and prolong survival.