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对8只右肾结石犬和45只独肾家兔进行体外冲击波碎石(ESWL)实验,以评价低能量体外冲击波碎石效果及比较冲击波能量不同对肾脏的损伤程度。结果表明,低能量体外冲击波碎石效果与高能量相比无明显差异,且对肾脏的损伤程度明显轻于高能量冲击波。体外冲击波能量的高低与肾脏的损伤程度之间呈显著的正相关(r=0.8573,P<0.05);临床应用高能量ESWL治疗上尿路结石795例,碎石成功率98.11%,平均碎石次数1.49次/例,用低能量ESWL治疗上尿路结石248例,成功率97.17%,平均1.58次/例,两者相比均无显著性差异(P>0.05)。低能量体外冲击波碎石病人与高能量碎石相比具有术中反应轻,术后血尿发生率低,程度轻,麻醉药用量少和无严重并发症等优点。
Eight ESWL dogs and 45 kidney kidneys were subjected to ESWL to evaluate the effect of low energy extracorporeal shock wave lithotripsy and to compare the effects of different shock wave energy on kidney damage. The results show that low-energy extracorporeal shock wave lithotripsy results compared with high-energy no significant difference, and the degree of damage to the kidneys was significantly lighter than the high-energy shock wave. The energy of extracorporeal shock wave was positively correlated with the degree of renal damage (r = 0.8573, P <0.05). The clinical application of high energy ESWL in treatment of upper urinary calculi in 795 cases, the success rate of gravel 98. 11%, the average number of gravel 1.49 times / cases, with low-energy ESWL treatment of 248 cases of upper urinary tract stones, the success rate of 97.17%, an average of 1.58 times / cases, both no significant difference (P> 0.05). Low-energy extracorporeal shock wave lithotripsy compared with high-energy gravel has the advantages of intraoperative response, low incidence of postoperative hematuria, light degree, less dosage of anesthetic and no serious complications.