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目的 :为进一步证实庚型肝炎病毒的感染途径 ,并探讨检测该病毒在献血员筛选工作中的意义。方法 :采用ELISA和PCR法 ,检测 76名血液病患者、82名非血液病患者和 90名健康体检者血清中乙、丙、庚型肝炎病毒感染标志物。结果 :这 3型病毒感染标志物的阳性率 (ELISA法 )在上述 3组人中分别为 2 6 .3%、12 .2 %和 10 .0 % ,11.8%、3.7%和 2 .2 % ,以及9.2 %、1.2 %和 1.1% ,血液病组显著高于另 2组 (χ2 =32 .36 ,P <0 .0 0 5 ) ;PCR法检查结果类似 ;有受血史者高于无受血史者 ,且与受血量呈正相关。结论 :庚型与乙、丙型肝炎病毒类似 ,可通过血液途径传播 ,因此对献血员采用高敏感性的筛选手段及严格控制输血指征 ,对控制庚型等可经血液传播的肝炎病毒的院内感染 ,具有重要意义
Objective: To further confirm the pathogen of hepatitis G virus infection, and explore the detection of the virus in blood donors screening significance. Methods: Serum levels of hepatitis B, C and G hepatitis B virus markers were detected in 76 blood disease patients, 82 non-hematological disease patients and 90 healthy subjects by ELISA and PCR. Results: The positive rates of these 3 virus infection markers (ELISA method) were 26.3%, 12.2% and 10.0%, 11.8%, 3.7% and 2.2% , And 9.2%, 1.2% and 1.1% respectively. The blood disease group was significantly higher than the other two groups (χ2 = 32.36, P <0.05). The PCR results were similar. Those who suffered from blood flow were positively correlated with the amount of blood taken. Conclusion: G-type is similar to hepatitis B and C viruses and can be transmitted through the blood. Therefore, high-sensitivity screening methods for blood donors and strict control of blood transfusion indications are needed to control G-type Hepatitis B virus Nosocomial infection, is of great significance