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环丙沙星(Ciprofloxacin,环丙氟哌酸)为合成的第三代喹诺酮类药物。具有抗菌谱广、杀菌力强、起效迅速等特点,近年来广泛用于临床。随着临床对本品的广泛应用,其不良反应有诸多报道,现综述如下1 引起神经毒性症状 环丙沙星引起神经毒性症状的发生率为1.6%,临床主要表现有头痛、头昏、眩晕、步态不稳、思睡、坐立不安、震颤、惊厥、精神错乱、恐怖、攻击性和幻觉、失眠、耳鸣等。其作用机制目前有三种
Ciprofloxacin (Ciprofloxacin) is a synthetic third-generation quinolone. With broad antibacterial spectrum, bactericidal power, rapid onset and so on, in recent years widely used in clinical. With the clinical application of this product widely, there are many reports of adverse reactions, are summarized as follows 1 The symptoms of neurotoxicity caused by ciprofloxacin neurotoxicity caused by the incidence of 1.6%, the main clinical manifestations of headache, dizziness, dizziness , Unstable gait, asleep, restlessness, tremors, convulsions, confusion, horror, aggression and hallucinations, insomnia, tinnitus and the like. There are currently three mechanisms of action