论文部分内容阅读
肝细胞癌手术切除复发率高是进一步提高疗效的重大障碍。复发是涉及肝癌多中心发生和侵袭转移每一阶段的复杂过程，影响肿瘤复发的因素不仅涉及肿瘤本身的生物学特性并与肝脏组织有关。实验性干预研究表明生物治疗、根据转移复发的分子机理所应用的新的疗法、药物可能是重要方向，而抗肿瘤血管生成治疗对肝癌转移复发的预防有特殊意义。
The high recurrence rate of surgical resection of hepatocellular carcinoma is a major obstacle to further improve the efficacy. Recurrence is a complex process involving multiple stages of liver cancer, invasion, and metastasis. The factors affecting tumor recurrence are not only related to the biological characteristics of the tumor itself, but also related to liver tissue. Experimental intervention studies have shown that biotherapy, new therapies and drugs based on molecular mechanisms of metastasis recurrence may be important directions, and antiangiogenic therapy has special significance for the prevention of metastasis and recurrence of liver cancer.