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目的 :探讨心内膜弹力纤维增生症 (EFE)患儿治疗前、后的心功能状态及评价治疗效果。方法 :对 10例临床恢复或好转的心电图及胸片结果与超声心动图检测的左心功能进行比较。初、复诊各以 10例健康儿作为对照组。结果 :治疗前左室舒张末内径 (L VDd)、左室射血分数 (L VEF)、左室射血前期 (L VPEP)、 E峰间隔分开 (ESPP)均明显异常 ;治疗后症状明显好转 ,9/ 10例心功能指数 L VEF、缩短分数 (FS)达正常范围 ,但与正常对照比较仍有 L VEF、 FS偏低 ,EPSS、 L VPEP升高 ,左室收缩期壁应力 (ESWS)降低 ,L VDd增大。结论 :EFE临床恢复标准不能仅依赖临床症状、心电图及胸片恢复或好转 ,更需根据其左心功能、L VDd的测量作综合评价。
Objective: To investigate the cardiac function of children with endocardial fibroelastosis (EFE) before and after treatment and evaluate the therapeutic effect. Methods: 10 cases of clinical recovery or improvement of electrocardiogram and chest X-ray results compared with echocardiography. At the beginning and follow-up, 10 healthy children were used as the control group. Results: Left ventricular end-diastolic diameter (LVDd), left ventricular ejection fraction (L VEF), pre-left ventricular ejection fraction (L VPEP) and ESP peak separation were significantly different before treatment; (LVEF), 9/10 heart function index (LVEF) and shortening score (FS) were all within the normal range. However, compared with the normal control group, there were still L VEF, low FS, increased EPSS and L VPEP, left ventricular systolic wall stress (ESWS) Reduce, L VDd increase. Conclusion: The clinical recovery criteria of EFE can not only depend on the clinical symptoms, ECG and chest X-ray recovery or improvement, but also based on its left ventricular function, LVDd measurement for comprehensive evaluation.