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目的探究判断肺部曲霉菌感染的微生物检验方法以及肺部曲霉菌感染的相关临床表现。方法选取2014年6月-2015年6月于我院就诊,肺部曲霉菌检查结果呈现阳性的162例患者作为研究对象,对患者进行相关的微生物检验并且分析其临床表现。结果组织病理切片显示,肺部曲霉菌分为两种类型,分别是寄生型和侵袭型。经GM试验检测可发现寄生型阳性率为75.25%,侵袭型阳性率为77.05%;通过G试验检测发现寄生型阳性率为58.42%,侵袭型阳性率为63.93%;通过对患者的痰液进行培养,发现寄生型阳性率为44.55%,侵袭型阳性率为31.15%。表明微生物检查方法中GM试验的准确度较高,而痰液培养的准确度最低。因此在进行微生物检查时需要多种检查同时检测,以提高阳性检出率的准确性。对于肺部曲霉菌感染的患者而言,常见的临床特征主要为发热、咳嗽、咯血、啰音以及呼吸困难等,其中寄生型患者最常见的表现为咯血,侵袭型患者主要表现为除咯血外的其他临床特征。结论通过对肺部曲霉菌感染的微生物检验和临床诊断进行分析,有助于对患者进一步确诊,帮助患者及早进行后期治疗,保障患者的生命安全。
Objective To explore the method of microorganism testing to judge the pulmonary aspergillus infection and the related clinical manifestations of pulmonary aspergillus infection. Methods A total of 162 patients with positive pulmonary aspergillosis who were seen in our hospital from June 2014 to June 2015 were enrolled in this study. The related microorganisms were examined and their clinical manifestations were analyzed. Results Histopathology showed that Aspergillus sp. Was divided into two types, parasitic and invasive. The GM test showed that the positive rate of parasitic was 75.25% and the positive rate of invasive was 77.05%. The positive rate of parasitic positive was 58.42% and the aggressive positive rate was 63.93% by G test. Cultivation, found that the positive rate of parasitic was 44.55%, invasive positive rate was 31.15%. This indicates that the accuracy of the GM test in the microbial test method is high, while the sputum culture has the lowest accuracy. Therefore, in the microbiological examination requires a variety of tests at the same time testing, in order to improve the accuracy of the positive detection rate. For patients with pulmonary aspergillosis, the common clinical features are fever, cough, hemoptysis, auscultation and dyspnea, etc. Among them, the most common manifestation of parasitic patients is hemoptysis, and the aggressive patients are mainly manifested as hemoptysis Other clinical features. Conclusion The microbiological examination and clinical diagnosis of pulmonary aspergillosis infection are helpful to further diagnose the patients and help the patients to take early treatment as soon as possible to ensure the patient’s life safety.