“难治性肾病综合征”被日本厚生省进行性肾障碍调查研究组定义为 :在应用了包括肾上腺皮质类固醇激素及免疫抑制剂合用的诸种治疗后 ,6个月仍不见缓解 ,也达不到不完全缓解 型的肾病综合征。这里的“完全缓解”是指“蛋白尿消失、血清蛋白正常化、临床各种症状消失。”而“不 “Refractory nephrotic syndrome” is defined by the Japanese Ministry of Health and Personality Research into Kidney Disorder: The study group, defined as having no relief at 6 months after treatment with various treatments including adrenocortical steroid hormones and immunosuppressive agents, also failed to achieve To incomplete remission of nephrotic syndrome. Here, “complete remission” means “disappearance of proteinuria, normalization of serum proteins, disappearance of various clinical symptoms.” "No