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目的了解无肝素透析治疗维持性血液透析的尿毒症患者并发颅内出血的疗效及其转归。方法回顾性分析总结我院1999年1月至2007年6月,采用无肝素透析治疗维持性血液透析的尿毒症患者并发颅内出血16例,了解其发病诱因及无肝素透析治疗尿毒症并发颅内出血的疗效及其转归。结果16例尿毒症合并颅内出血患者中,11例出血得到控制,病情改善,其中4例留有不同程度肢体活动障碍,7例无肢体功能障碍基本恢复出院;5例死亡,病死率31.3%。结论无肝素透析可明显降低维持性血液透析的尿毒症患者并发颅内出血的病死率;低分子肝素在血液透析中应用,可降低脑出血的发生率。
Objective To investigate the curative effect and outcome of intracranial hemorrhage complicated with uremia without hemodialysis in maintenance hemodialysis patients. Methods Retrospective analysis of our hospital from January 1999 to June 2007, non-heparin dialysis treatment of hemodialysis patients with uremia complicated by intracranial hemorrhage in 16 cases, to understand the incidence of incentives and no heparin dialysis treatment of uremia complicated by intracranial hemorrhage The efficacy and outcome. Results Of the 16 patients with uremia complicated with intracranial hemorrhage, 11 cases of hemorrhage were controlled and the condition was improved. Among them, 4 cases had limb movement disorders with varying degrees and 7 cases without limb dysfunction were basically discharged. 5 cases died and the case fatality rate was 31.3%. Conclusion Heparin-free dialysis can significantly reduce the mortality of patients with hemodialysis uremia complicated by intracranial hemorrhage; low molecular weight heparin in hemodialysis can reduce the incidence of cerebral hemorrhage.