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目的：评价最大呼气流速—容量曲线的临床意义。方法：选择慢性支气管炎、支气管哮喘、支气管扩张、肺间质病变等疾病患者共１７７４例，按ＦＥＶ１％及ＶＣ％分为常规肺功能正常组和异常组，观察两组的小气道功能。小气道功能异常按单纯Ｖ５０或Ｖ２５小于预计值的７０％判断为异常。结果：常规肺功能异常组中，ＭＥＦＶＣ异常率为９２．４％。在常规肺功能正常组中，近２／３的最大呼气流量－容积曲线（ＭＥＦＶＣ）已有异常。结论：常规肺功能正常的患者，ＭＥＦＶＣ对早期诊断小气道功能异常确实具有实际的临床意义。疾病的早期（常规肺功能正常时）ＭＥＦＶＣ的异常首先表现为Ｖ５０的降低。常规肺功能异常时，ＭＥＦＶＣ的检测已无意义。常规肺功能异常而ＭＥＦＶＣ正常者，应考虑到是否有肺间质病变的存在
PURPOSE: To evaluate the clinical significance of the maximal expiratory flow-volume curve. Methods: A total of 1774 patients with chronic bronchitis, bronchial asthma, bronchiectasis and interstitial lung disease were selected and divided into two groups according to FEV1% and VC%, respectively. The normal airway function and abnormal group were observed. Small airway dysfunction by simple V50 or V25 less than 70% of the expected value is judged to be abnormal. Results: The abnormal rate of MEFVC was 92.4% in routine pulmonary dysfunction group. Nearly two-thirds of the maximum expiratory flow volume-volume curve (MEFVC) was abnormal in the normal lung function group. Conclusion: MEFVC has practical clinical significance in the early diagnosis of small airway dysfunction in patients with normal pulmonary function. Early disease (normal lung function is normal) MEFVC abnormalities first showed a decrease in V50. MEFVC testing is meaningless when routine lung function is abnormal. Conventional pulmonary dysfunction and normal MEFVC, should be considered whether there is the existence of interstitial lung disease