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目的:为了提高对肾细胞癌的认识,有利于治疗。方法:选择肾癌新鲜标本16例,其中透明细胞癌6例,颗粒细胞癌3例,嫌色细胞癌2例,集合管癌2例,乳头样癌2例,肉瘤样癌1例,常规光镜电镜观察。结果:肾癌组织类型多样,癌细胞形态不一,多呈实性巢状、管样或乳头状排列,间质少。不同类型细胞超微结构改变基本相同,仅脂滴、糖元和线粒体含量不同。结论:肾癌不同组织学类型与预后关系密切,组织发生可能来源于肾原基未分化干细胞。超微结构有助于低分化肾细胞癌的诊断及其远处转移性肾癌的确认。
Objective: In order to improve awareness of renal cell carcinoma, is conducive to treatment. Methods Sixteen fresh kidney cancer samples were selected, including 6 cases of clear cell carcinoma, 3 cases of granulosa cell carcinoma, 2 cases of chromophobe carcinoma, 2 cases of collecting duct carcinoma, 2 cases of papillary carcinoma, 1 case of sarcomatoid carcinoma, Microscopic observation. Results: There are many types of renal cell carcinoma with different morphological features of cancer cells, mostly solid nests, tube-like or papillary arrangement and few interstitial. The ultrastructural changes of different types of cells are basically the same, only lipid droplets, glycogen and mitochondria content are different. Conclusion: The different histological types of renal cell carcinoma are closely related to the prognosis. The occurrence of renal cell carcinoma may originate from undifferentiated kidney cells. Ultrastructure contributes to the diagnosis of poorly differentiated renal cell carcinoma and the confirmation of distant metastatic renal cell carcinoma.