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目的 :探讨子宫颈癌和外阴癌的AgNORs变化。 方法 :应用AgNORs自动图像分析系统 ,对 31例子宫颈癌、8例淋巴结转移灶及 11例外阴癌、3例淋巴结转移灶进行了AgNORs颗粒计数 ,并进行了统计学分析。 结果 :子宫颈癌和外阴癌的AgNORs颗粒计数与对照组相比显著增高 ,且随着组织分化程度的降低 ,AgNORs颗粒计数逐渐增多 ,并出现显著差异 ;发生淋巴结转移的宫颈癌原发灶 ,其AgNORs颗粒计数显著增高。结论 :AgNORs图像分析技术是一项较好的肿瘤辅助诊断方法 ,AgNORs颗粒计数对于下生殖道癌及其淋巴转移的诊断具有较好的临床应用价值
Objective: To investigate the changes of AgNORs in cervical cancer and vulvar cancer. Methods: AgNORs particle counting was performed on 31 cervical cancer cases, 8 cases of lymph node metastases, 11 cases of vulvar cancer and 3 cases of lymph node metastases by AgNORs automatic image analysis system. The statistical analysis was carried out. Results: AgNORs particle counts of cervical cancer and vulvar cancer were significantly higher than that of the control group, and with the decrease of the degree of differentiation, AgNORs particle counts gradually increased and showed significant difference. The primary tumor of cervical cancer with lymph node metastasis, The AgNORs particle counts were significantly higher. Conclusion: The AgNORs image analysis technique is a good method of tumor-assisted diagnosis. The particle counts of AgNORs have a good clinical value for the diagnosis of lower genital tract cancer and lymphatic metastasis