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目的 了解妊娠妇女中、晚孕铁缺乏及贫血状况。方法中期单胎妊娠孕妇95例,排除地中海贫血及其它特殊病史后,于16~24 w检测并记录以下指标:血清铁二项,包括血清铁蛋白(serum ferritsn,SF)、血清铁(serum iron,SI);血常规,包括红细胞计数(Red blood count,RBC)、红细胞比容积(Hematocrit,HCT)、血红蛋白(Hemoglobin,Hb)、网织红细胞(RET)。晚期妊娠28~30W,复查血清铁二项和血常规,对于出现贫血的患者进行补铁治疗,并于37~39 w再次检测血清铁二项和血常规。结果随着孕周增大,晚期妊娠(28~30 w)与中期妊娠(16~24 w)进行比较,血清铁二项及血常规指标均呈现下降状况,SF、SI、RBC、HCT、Hb差异有统计学意义(P<0.05)。进行补铁治疗后,37~39W孕妇,SF、SI、RBC、HCT、Hb等指标明显改善。结论血清SF、SI可用于检测妊娠妇女铁缺乏状况,妊娠晚期孕妇易出现缺铁性贫血,应适时使用补铁药物进行干预。
Objective To understand the pregnant women, iron deficiency in late pregnancy and anemia. Methods Ninety-five pregnant women with singleton pregnancies were enrolled in this study. After excluding the history of thalassemia and other special medical conditions, the following indicators were detected and recorded at 16-24 w: serum iron binders including serum ferritsn (SF), serum iron , SI), and blood routine including Red Blood Count (RBC), Hematocrit (HCT), Hemoglobin (Hb) and Reticulocyte (RET). Late pregnancy 28 ~ 30W, review of serum iron and blood routine, patients with anemia for iron treatment, and in 37 ~ 39 w again test serum iron two and blood. Results Compared with the second trimester pregnancy (28-30 w) and the second trimester pregnancy (16-24 w), the serum iron binomial and hematological indexes decreased with the gestational age increasing. The levels of SF, SI, RBC, HCT, Hb The difference was statistically significant (P <0.05). After iron treatment, 37 ~ 39W pregnant women, SF, SI, RBC, HCT, Hb and other indicators significantly improved. Conclusion Serum SF, SI can be used to detect iron deficiency in pregnant women, pregnant women prone to iron deficiency anemia in late pregnancy should be timely intervention with iron drugs.