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目的观察慢性肺源性心脏病患者治疗前后血清肌钙蛋白的变化及其临床意义。方法分别检测58例慢性肺源性心脏病患者急性期住院患者,入院时及出院时的血清肌钙蛋白并与40例对照组比较。结果血清肌钙蛋白治疗后较治疗前明显降低(P<0.05),但仍然高于健康对照组(P<0.05)。结论血清肌钙蛋白能反映慢性肺源性心脏病心肌损害的严重程度,表明是慢性肺源性心脏病病情严重程度的监测指标。
Objective To observe the changes of serum troponin in patients with chronic cor pulmonale before and after treatment and its clinical significance. Methods Fifty-eight patients with chronic cor pulmonale were enrolled in the study. The serum levels of troponin at admission and at discharge were compared with those of 40 control subjects. Results Serum troponin after treatment was significantly lower than before treatment (P <0.05), but still higher than the healthy control group (P <0.05). Conclusion Serum troponin can reflect the severity of myocardial damage in patients with chronic cor pulmonale, indicating that it is a monitoring indicator of the severity of chronic cor pulmonale.