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近年来,由于新药和新制剂的品种不断增加,出現了一些作用类似的药物。有些医药工作者,往往錯认为它們就是一种东西,或者认为差异不大,因而在配方工作中常发生有彼此代用的情况。但是,这些药品和制剂从药理性质或某些成分、含量上来看,它們之間多少还是有所不同的,应引起注意。一、有些药品它們虽然类似,但毒性和副作用却有不同,不可随便互相代用。例如,鏈霉素和双氢鍵霉素的盐,它們的毒性和副作用是有不同的,双氢鏈霉素对第八对脑神经(听觉神經)的損害比鏈霉素重,在引起耳聋时无先兆症状,且在停药后出现,一般难于恢复,所以不宜于长期使用。双氢鏈霉素的刺激性較强,故忌作脑池和鞘内注射。鏈霉素在使用过程中,可能出现面部麻木感,在稳定性方面比双氢鏈霉素差。因
In recent years, with the increasing variety of new drugs and new preparations, a number of similar drugs have emerged. Some medical workers often mistakenly think that they are one kind of thing or they think that they are not very different and therefore often substitute each other in formulating work. However, these drugs and preparations from the pharmacological properties or some composition, content point of view, how much or how much different between them should be noted. First, some of their drugs although similar, but the toxicity and side effects are different, can not be replaced with each other. For example, the salts of streptomycin and dihydrostnylamin are different in their toxicity and side effects. Dihydrostreptomycin harms the eighth cranial nerve (auditory nerve) more than streptomycin and causes deafness When no aura symptoms, and appear after stopping, generally difficult to recover, it is not suitable for long-term use. Dihydrogen streptomycin irritation, it is forbidden to make cerebral pool and intrathecal injection. Streptomycin in the course of use, facial numbness may appear, in terms of stability than dihydrostreptomycin. because