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目的探讨代谢性疾病肥胖、血糖异常、血脂异常与高尿酸血症(HUA)之间的关系,为HUA的健康管理提供科学依据。方法以2011年来我院健康体检的19805人为研究对象,采用身高体重电子测量仪测量体检人员的身高、体质量,计算BMI;清晨空腹常规静脉采血,检测UA、TC、TG、HDL、LDL和Glu,对该人群的血尿酸(UA)、Glu、血脂[总胆固醇(TC)、三酰甘油(TG)、高密度脂蛋白(HDL)、低密度脂蛋白(LDL)]等检查结果进行统计分析。结果 BMI分布、Glu异常、血脂异常的发生率在HUA组和正常尿酸组之间的差异均有统计学意义(P<0.01)。HUA组BMI、Glu水平、TC、TG、LDL水平均明显高于正常尿酸组,HDL水平则明显低于正常尿酸组,各组间差异均有统计学意义(P<0.01)。结论 HUA患者比尿酸正常人群更易发生超重、肥胖、Glu及血脂代谢异常。
Objective To investigate the relationship between metabolic diseases such as obesity, abnormal blood glucose, dyslipidemia and hyperuricemia (HUA), and to provide a scientific basis for the health management of HUA. Methods The 19805 people in our hospital for physical examination in 2011 were enrolled in this study. The height and body mass of the medical staff were measured by height and weight electronic measuring instrument to calculate the BMI. UA, TC, TG, HDL, LDL and Glu The results of UA, Glu, TG, TG, HDL and LDL were statistically analyzed . Results The distribution of BMI, Glu abnormality, the incidence of dyslipidemia in HUA group and normal uric acid group were significantly different (P <0.01). The levels of BMI, Glu, TC, TG and LDL in HUA group were significantly higher than those in normal uric acid group, while the levels of HDL in HUA group were significantly lower than those in normal uric acid group (P <0.01). Conclusion HUA patients are more prone to overweight, obesity, Glu and dyslipidemia than normal uric acid.