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目的:了解西安市美沙酮维持治疗门诊受治人群丙型肝炎病毒(HCV)感染现状及其特点,为制订相应的干预措施提供科学依据。方法:对西安市美沙酮维持治疗门诊(MMT)2007年5月1日至2008年5月31日入组的404名海洛因依赖者进行问卷调查,并采静脉血检测抗-HCV抗体。结果:404名吸毒者中,抗-HCV阳性率为60.6%。静脉注射史中,曾静脉注射吸毒者280人,抗-HCV阳性率为75.4%,高于非静脉吸毒者的27.4%,差异有统计学意义(P<0.01)。有14人曾共用注射器具,占3.5%(14/404)。共用注射器具的感染率为78.6%。未共用注射器具者的HCV感染率为60.0%。多性伴者HCV感染率明显高于单一性伴或无性伴者,P<0.01,有统计学意义。结论:西安市海洛因依赖人群HCV感染率高,相关危险行为普遍存在。
Objective: To understand the current status and characteristics of hepatitis C virus (HCV) infection in methadone maintenance treatment outpatient clinics in Xi’an and provide a scientific basis for formulating corresponding intervention measures. Methods: A total of 404 heroin addicts admitted to the methadone maintenance treatment clinic (MMT) in Xi’an from May 1, 2007 to May 31, 2008 were surveyed and venous blood samples were collected for the detection of anti-HCV antibodies. Results: Among 404 drug addicts, the positive rate of anti-HCV was 60.6%. In the history of intravenous injection, there were 280 intravenous drug users who were intravenously injected, and the positive rate of anti-HCV was 75.4%, which was higher than that of non-intravenous drug users (27.4%, P <0.01). Fourteen people had shared injecting equipment, accounting for 3.5% (14/404). The prevalence of common syringes was 78.6%. The HCV infection rate of non-sharing syringes was 60.0%. The infection rate of HCV in multi-partner was significantly higher than that in single partner or non-partner, P <0.01, with statistical significance. Conclusion: The heroin addicts in Xi’an have a high prevalence of HCV infection and dangerous behaviors are common.