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本文应用彩色多普勒技术检测72例Ⅱ型糖尿病（DM）患者的球后血流动力学改变，包括眼动脉（OA）、视网膜中央动脉（CRA）。结果显示在糖尿病性视网膜病变（DR）发生过程的极早期阶段、眼底荧光造影尚未发现明显病变时，CRA血流速度较对照组增高（P＜0．05），背景型DR早期阶段接近对照组（p＞0．05），增殖前期、增殖期低于对照组（p＜0．05）并伴有OA舒张未期血流速度下降及阻力指数增高；DM不伴DR者或DR早期CRA血流速度与空腹血糖水平呈正相关，视网膜病变越重血糖水平对CRA血流速度的影响越小。提示DM患者的眼部血流动力学变化与DR发生、发展之间的关系是相当复杂的；它反映了视网膜微循环对高血糖等全身与局部代谢异常的代偿与失代偿变化。
In this paper, hemodynamic changes in 72 patients with type 2 diabetes mellitus (DM), including ophthalmic artery (OA) and central retinal artery (CRA), were detected by color Doppler imaging. The results showed that in the very early stages of the development of diabetic retinopathy (DR), no obvious pathological changes were found in the fundus fluorescein angiography, and CRA blood flow velocity was higher than that in the control group (P <0.05). In the early stage of background DR, (P> 0.05). In the early stage of proliferation, the proliferative phase was lower than that of the control group (p <0.05), with the decrease of blood flow velocity and the increase of resistance index Flow velocity and fasting blood glucose levels were positively correlated, the more severe retinal lesion blood glucose levels CRA blood flow velocity less. It is suggested that the relationship between the ophthalmic hemodynamic changes and the occurrence and development of DR in DM patients is quite complex. It reflects the compensatory and decompensated changes of systemic and local metabolic abnormalities such as hyperglycemia in the retina microcirculation.