阻塞性睡眠呼吸暂停(Obstructive sleep spenea,OSA)系指口鼻气流停止,胸腹式呼吸运动仍存在。呼吸暂停系指气道开始关闭至醒觉后终止。醒觉伴随气道重新开放而终止呼吸暂停的持续为该综台征的主要基本原理。引起醒觉的刺激尚不清楚,但可能与低氧血症或高碳酸血症刺激周围化学感受器引起上气道反射或增加呼吸肌肉驱动力克服阻塞所致。 OSA通常以呼吸暂停次数,呼吸暂停时间和氧饱和度为特点的呼吸异常。呼吸暂停次数与呼吸暂停起始机制最相关,而呼吸暂停持续时间与气道重新开放或呼吸暂停终止机制有关,氧饱和度下降范围与呼吸 Obstructive sleep apnea (OSA) refers to the stop of nasal air flow, chest and abdomen respiratory movement still exists. Apnea refers to the airway begins to close to wake up after termination. Awareness of the continuation of the continuation of apnea as the airway is reopened is the primary rationale behind the syndrome. The stimuli that cause arousal are unclear, but may be overcome with hypoxemia or hypercapnia by stimulating the surrounding chemoreceptors to cause upper airway reflex or increasing respiratory muscle drive over obstruction. OSA is usually characterized by respiratory arrest, apnea time and oxygen saturation. The number of apneas is most relevant to the apnea initiating mechanism, and the duration of apnea is related to airway reopening or apnea termination mechanisms, the range of oxygen saturation descent and breathing