用酶联法测定４１８例女性乳腺癌病人术前血清ＣＥＡ值，将病人分为ＣＥＡ正常组和异常组，根据临床分析选择术式和辅助化疗方案，全部病例均行随访。χ２检验证实ＣＥＡ异常组病期较晚（Ｐ＜０００５）。ＳＰＳＳＷｉｎｄｏｗｓ６０软件Ｌｏｇ－Ｒａｎｋ检验结果两组病人生存率差异极为显著（Ｐ＜０００１），Ｃｏｘ模型回归分析表明术前血清ＣＥＡ，腋窝淋巴状况及肿瘤大小均与长期生存相关，近似相对危险度分别为０５４４１、１２５２０和２１１０１。提示术前血清ＣＥＡ水平可以作为评估乳腺癌预后的一项指标 The preoperative serum CEA values ​​of 418 women with breast cancer were measured by enzyme-linked immunosorbent assay (ELISA). The patients were divided into normal and abnormal CEA groups. All patients were followed up according to clinical analysis. Χ2 test confirmed that the abnormal CEA group had a relatively late stage (P<0005). The Log-Rank test results of SPSSWindows60 software showed a significant difference in survival rate between the two groups (P<0001). Regression analysis of Cox model showed that preoperative serum CEA, axillary lymph status, and tumor size were all associated with long-term survival, and were relatively dangerous. The degrees are respectively 05441, 12520 and 21101. Preoperative serum CEA levels can be used as an indicator to evaluate the prognosis of breast cancer