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目的探讨肩胛舌骨上颈淋巴清扫术在口腔癌患者治疗的应用效果。方法选择本院2010年4月—2015年2月100例口腔癌患者,根据数字表法随机分组为C组及S组各50例,C组术型为传统颈淋巴根治性清扫术;S组术型为肩胛舌骨上颈淋巴清扫术。对比分析两组患者术后3、6个月的生存率及复发率的差异,并对两组术后的生存质量进行评估。计量资料比较采用t检验,计数资料比较采用χ2检验,P<0.05为差异有统计学意义。结果两组患者生理功能、心理功能、疼痛情况、健康情况、生命力、社会功能、情感功能、身体健康评分[(44.29±15.91)、(40.58±16.92)、(39.65±9.31)、(41.32±21.32)、(43.76±24.37)、(40.68±8.49)、(39.28±18.41)、(43.27±16.49)分与(51.22±11.38)、(66.58±26.33)、(46.58±13.28)、(55.67±16.59)、(55.39±18.21)、(54.58±11.31)、(55.89±26.32)、(51.28±11.65)分]比较,差异均有统计学意义(均P<0.05)。结论肩胛舌骨上颈淋巴清扫术有利于患者术后生存质量的提升,在临床上可取代传统颈淋巴根治性清扫术。
Objective To investigate the effect of supraomohyoid neck lymph dissection in the treatment of oral cancer patients. Methods 100 cases of oral cancer from April 2010 to February 2015 in our hospital were randomly divided into three groups: group C (50 cases) and group S (50 cases). The patients in group C were treated by radical neck dissection. Group S Surgery for the supraomohyoid neck lymph dissection. The difference of survival rate and recurrence rate between the two groups were compared and analyzed 3 and 6 months after operation, and the quality of life was evaluated after operation. Measurement data were compared using t test, count data were compared using χ2 test, P <0.05 for the difference was statistically significant. Results The scores of physical function, psychological function, pain, health, vitality, social function, emotional function, physical health score in the two groups were significantly higher than those in the control group [(44.29 ± 15.91), (40.58 ± 16.92), (39.65 ± 9.31), (41.32 ± 21.32 (43.76 ± 24.37), (40.68 ± 8.49), (39.28 ± 18.41), (43.27 ± 16.49) and (51.22 ± 11.38), (66.58 ± 26.33), (46.58 ± 13.28) and (55.67 ± 16.59) , (55.39 ± 18.21), (54.58 ± 11.31), (55.89 ± 26.32) and (51.28 ± 11.65) points respectively. All the differences were statistically significant (all P <0.05). Conclusion The supraomohyoid lymphadenectomy is helpful to improve the quality of life of patients, which can replace the traditional radical neck dissection in clinic.