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本文以4075名儿童为对照观察对象,探讨日本冻干皮内卡介苗在常温条件下保存对其接种的阳转效果的影响。研究结果表明,在月平均温度14.4～25.9℃间保存6个月活菌数为653.5万/mg,12周阳转率90.1％,结素均径10.9mm。作者认为,冷链设备较差地区除新生儿初种外,可选气温适宜月份试行菌苗“常温保存”,短时间完成大量学龄儿童复种工作,无须为冷链设备而耗费巨资,亦可获得颇为满意的免疫效果。
In this paper, 4075 children as a control object to investigate the Japanese freeze-dried intradermal BCG vaccination preservation at room temperature on the positive effects of vaccination. The results showed that the viable count of 6 months in the monthly average temperature of 14.4 ~ 25.9 ℃ was 6.535 million / mg, the positive rate of 90.12% in 12 weeks and the average diameter of 10.4 mm in nodules. The author believes that the cold chain equipment in poor areas in addition to the newborn newborn, the optional temperature suitable for trial of the month bacillus vaccine “room temperature preservation”, a short time to complete a large number of school-age children re-planting work, without having to spend huge amounts of money for the cold chain equipment, Get quite satisfactory immune effect.