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目的探讨由磺胺嘧啶银治疗创面转换为湿润暴露疗法的治疗效果。方法对2007年3月～20 1 2年3月收治的7 2例使用磺胺嘧啶银处理的烧伤创面,分别采用立即、分区及延迟转换为湿润暴露疗法治疗,对伤后4 8 h的创面,清洗磺胺嘧啶银后立即完成治疗方法的转换,对已成痂、溶痂的创面则根据其烧伤创面的基本情况如创面的深度、面积以及创面炎症情况等,分别采用立即、分区及延迟转换的处理方式。立即转换者4 9例,分区转换者1 8例,延迟转换者5例。结果 7 2例烧伤患者全部治愈,4 9例立即转换的患者在伤后1 4～3 5 d治愈并出院;23例采用分区转换和延迟转换的患者在对深度烧伤创面实施了清创植皮术治疗,经过抗炎、营养支持等综合治疗后于28～5 6 d创面愈合并出院。结论对伤后4 8 h内入院的使用磺胺嘧啶银的患者可以采用立即转换处理,其治疗效果与常规湿润暴露疗法相似;对于创面较重的患者且使用4 8 h以上的患者采用延迟转换处理,与磺胺嘧啶银干燥暴露疗法治疗结果相似。
Objective To investigate the therapeutic effect of silver sulfadiazine treated wounds converted to moisturizing exposure therapy. Methods 72 cases of burn wounds treated with silver sulfadiazine were treated with immediate, regional and delayed conversion to moisturizing exposure therapy. The wounds, Immediately after the cleaning silver sulfadiazine conversion of treatment methods, has become a scab, the dissolution of the crust wound according to the basic situation of its burn wounds such as the depth of the wound, the area and the wound inflammation, respectively, using the immediate, zoning and delayed conversion Processing method. 49 cases were immediately converted, 18 cases were zoned conversion, and 5 cases were delayed conversion. Results All 72 cases of burn patients were cured, 49 cases of immediate conversion were cured and discharged from 14 to 35 days after injury. In 23 cases of patients who underwent regional and delayed conversion, debridement skin grafting was performed on deep burn wounds After treatment, after anti-inflammatory, nutritional support and other comprehensive treatment of 28 ~ 56 days wound healing and discharge. CONCLUSIONS: Patients treated with silver sulfadiazine admitted within 48 h after injury may be treated with immediate conversion therapy, which is similar in efficacy to conventional moisturizing exposure therapy. In patients with severe wounds and those with more than 48 h, delayed conversion is used , And silver sulfadiazine dry exposure therapy treatment results are similar.