过敏性紫癜(又名Henoch—Schonlein综合征)是以全身毛细血管炎为主要病理损害的过敏性疾病。通常为皮肤紫癜伴有不同程度的水肿、关节炎、胃肠道和肾脏出血的临床表现。其他器官和系统,如中枢神经系统,呼吸道和心脏受累极少。 19世纪初Willam对本病作了描述。1837年Schonlein首先认识到紫癜和关节症状的连系。1874年Henoch报告了第一个儿童病例,并强调胃肠道症状。1915年Frank首先应用过敏 Henoch-Schonlein syndrome Henoch-Schonlein syndrome is an allergic disease characterized by systemic capillary inflammation as the main pathological lesion. Skin purpura usually associated with varying degrees of edema, arthritis, gastrointestinal and renal bleeding clinical manifestations. Other organs and systems, such as the central nervous system, respiratory and cardiac involvement rarely. Willam described the disease early in the 19th century. In 1837 Schonlein first recognized the link between purpura and joint symptoms. In 1874 Henoch reported the first case of children and emphasized gastrointestinal symptoms. 1915 Frank first application of allergy