Fipronil is a phenylpyrrole insecticide that is widely used to control a variety of pests associated with crops in both agricultural and non-agricultural areas[1]. In the natural environment, fipronil can degrade to fipronil-desulfinyl, fipronil-sulfone, or fipronil-sulfide by photolysis, oxidation, or reduction, and these metabolites are more toxic to animal tissue than the parent molecule[2]. In China, the use of fipronil in agricultural areas is forbidden except as a corn or other coatedeed treatment agent[3]. In June 2017, the Netherlands Food and Consumer Product Safety Authority (NVWA) found a high concentration of fipronil in a sample batch of eggs, which would undoubtedly have a serious impact on the health of consumers. In short, a reliable and rapid method for monitoring fipronil and its metabolites in eggs must be developed.