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目的观察稳心颗粒对心房颤动患者射频消融术后早期复发的影响。方法入选拟行房颤射频消融术的住院患者,其中试药组35例(稳心颗粒组)和对照组36例。患者射频消融术后常规给予胺碘酮和华法林,试药组加用稳心颗粒。观察两者入院时及术后3个月血清氨基末端B型钠尿肽原(NT-proBNP)水平、入院时及术后3个月左房内径大小及早期复发情况。结果试药组早期复发率为9%,对照组早期复发率为31%,两组比较差别有显著意义(P<0.05);术后3个月两组NT-proBNP水平及左房内径呈下降趋势,且试药组明显低于对照组(P<0.05)。结论稳心颗粒能够减少房颤射频术后早期复发,降低NT-proBNP水平及缩小左房内径。
Objective To observe the effect of Wenxinkeli on the early recurrence of patients with atrial fibrillation after radiofrequency catheter ablation. Methods Selected hospitalized patients undergoing radiofrequency ablation of atrial fibrillation, including 35 cases in the test group (Wenxin granule group) and 36 cases in the control group. Amiodarone and warfarin were given routinely after radiofrequency ablation in patients with stable heart particles. The levels of serum amino-terminal B-type natriuretic peptide (NT-proBNP) at admission and at 3 months after operation were observed. The size and early recurrence of left atrial diameter at admission and at 3 months after operation were observed. Results The early recurrence rate was 9% in the test group and 31% in the control group. The difference between the two groups was significant (P <0.05). The NT-proBNP level and the left atrial diameter of the two groups decreased after 3 months Trend, and the test group was significantly lower than the control group (P <0.05). Conclusion Wenxin Granule can reduce the early recurrence of AF after radiofrequency ablation, reduce the level of NT-proBNP and reduce the left atrial diameter.