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为探讨沙漠干热徒手应激行军时人体内一氧化氮合酶 (NOS)作用机理 ,对 74名沙漠干热环境中以不同速度和时间行军战士血浆NOS变化规律进行了研究。结果发现 ,3 5km /小时徒手应激行军时 ,NOS随行军时间的变化曲线呈右侧稍低的“钟”形 ;血浆NOS在最初 1小时内上升较快 ,大约1小时左右 ,NOS浓度开始下降 ,2小时后下降速度减慢 ;5km /小时徒手应激行军 ,NOS随行军时间的变化基本呈水平直线 ,血浆NOS在应激的最初 1小时内略下降 ,行军 1小时后下降速度加快 ,大约 2小时左右 ,下降到最低 ,此后NOS又缓慢上升 ,3小时左右上升到对照水平。结果提示 ,随着行军速度的增加 ,即应激强度的增加 ,机体用于介导和调节生理生化应激所消耗的NOS增加 ,尤其是最初 2小时内极为明显 ,行军 3小时后机体因应激诱导量激活NOS和用于介导和调节应激生理过程所消耗NOS量达到相对平衡。
To investigate the mechanism of nitric oxide synthase (NOS) in human body under dry-hot and cold-heading conditions in the desert, the changes of plasma NOS in marines at different speeds and times were studied in 74 desert hot and dry environments. The results showed that the curve of NOS was slightly lower on the right when the march was performed at 35km / h. The plasma NOS increased rapidly in the first hour, about 1 hour, and NOS concentration started And the descending speed slowed down after 2 hours. At 5 km / h, the march of hand-free stress was basically horizontal. The change of time of NOS was almost horizontal. The plasma NOS decreased slightly in the first hour of stress, About 2 hours or so, down to a minimum, then slowly rising NOS, 3 hours or so rose to the control level. The results suggest that with the increase of march speed, that is, the increase of stress intensity, the body used to mediate and regulate physiological and biochemical stress increased NOS, especially in the first 2 hours is extremely obvious, three hours after marching the body due to stress Induction of NOS activation and mediation and regulation of stress physiological processes consumed by the amount of NOS to achieve a relative balance.