论文部分内容阅读
目的探讨南涧县“云南不明原因猝死”与其他地区的区别,为制定切实有效的预防控制措施提供科学依据。方法对2002年和2004年发生在南涧县3起不明原因猝死疫情的流行病学资料、临床病历、实验室检测资料进行分析。结果3起不明原因猝死疫情累计死亡6人,均为家庭聚集性病例;对163例高危人群进行临床检诊和心电图检查,46%的人有头昏、恶心、乏力、心悸等症状,25%的人显示心电图异常,X线摄片心脏影不大;随机对27例作了血清CBV-IgM检测,阳性率为52%;采集主要粮食18份进行了硒含量测定,8份<0.01 mg/kg,4份在0.011～0.02 mg/kg,3份在0.021～0.03 mg/kg,2份在0.031～0.04 mg/kg,1份>0.04 mg/kg。结论南洞县为“云南不明原因猝死”病疫点;病区高危人群临床检诊、心电图检查结果与文献报道的其他地区研究结果相符,患者的心电图异常率稍偏高,南涧县病区在流行期人群柯萨奇B组病毒的感染水平普遍偏高,补硒可作为预防“云南不明原因猝死”病措施之一。
Objective To explore the difference between “sudden death of unknown causes in Yunnan Province” and other areas in Nanjian County and provide a scientific basis for formulating effective prevention and control measures. Methods The epidemiological data, clinical records and laboratory tests of 3 unidentified cases of sudden death in Nanjian County in 2002 and 2004 were analyzed. Results Six cases of sudden death from unidentified causes were all found in the family cluster. Clinical examination and electrocardiogram (ECG) were performed in 163 cases of high risk population, and 46% had symptoms of dizziness, nausea, fatigue, palpitations, 25% Of the people showed abnormal electrocardiogram, X-ray cardial heart shadow is not large; 27 cases were made of serum CBV-IgM detection was positive, the positive rate was 52%; collected 18 main food selenium content determination, 8 copies of <0.01 mg / kg, 0.011-0.02 mg / kg for 4 parts, 0.021-0.03 mg / kg for 3 parts, 0.031-0.04 mg / kg for 2 parts and> 0.04 mg / kg for 1 part. Conclusions South Dong County is the “Outbreak of Unidentified Sudden Death of Unidentified causes in Yunnan Province”. The clinical examination and electrocardiogram results of the high risk population in the ward are consistent with the findings of other regions reported in the literature. The abnormal rate of electrocardiogram in the patients is slightly higher. The prevalence of coxsackievirus B in the population is generally high, and selenium supplementation can be used as one of the measures to prevent sudden death from unidentified causes in Yunnan Province.