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Background and Purpose: Myasthenia gravis (MG) is considered as an autoimmane disease mediated by circulating antibodies against acetylcholine receptor (AChR).The thymus frequently shows abnormalities including hyperplasia and thymoma. The susceptibility to disease is likely to involve multiple genes, such as HLA haplotype, a subunit gene (CHRNA1), immunglobulin gene and T-Cell antigen receptor gene.The immunopathogenesis of MG has been clearly demonstrated by
Background and Purpose: Myasthenia gravis (MG) is considered as an autoimmane disease mediated by circulating antibodies against acetylcholine receptor (AChR). The thymus frequently shows abnormalities including hyperplasia and thymoma. The susceptibility to disease is likely to involve multiple genes, such as HLA haplotype, a subunit gene (CHRNA1), immunglobulin gene and T-Cell antigen receptor gene. The immunopathogenesis of MG has been clearly demonstrated by