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目的评价X线立体定向放射治疗在晚期胆管癌治疗中的价值。方法晚期胆管癌41例,胆肠内引流术后行立体定向放射治疗(SRT)16例,单纯行立体定向放射治疗15例,单纯行胆肠内引流术10例。X线立体定向放射治疗采用分次照射,方法为5Gy/次~6Gy/次,每周3次,总量达35Gy~36Gy。结果胆肠内引流术加立体定向放射治疗组、单纯立体定向放射治疗组及单纯胆肠内引流术组的1a生存率分别为63%、46.7%、0。结论胆肠内引流术加立体定向放射治疗晚期胆管癌疗效优于单纯立体定向放射治疗及单纯胆肠内引流
Objective To evaluate the value of X-ray stereotactic radiotherapy in the treatment of advanced cholangiocarcinoma. Methods 41 patients with advanced cholangiocarcinoma were treated with stereotactic radiosurgery (SRT) in 16 patients after choledochojejunostomy. 15 patients were treated with stereotactic radiotherapy alone and 10 patients were treated by choledochojejunostomy alone. X-ray stereotactic radiotherapy using fractionated irradiation, the method is 5Gy / times ~ 6Gy / times, three times a week, the total amount of 35Gy ~ 36Gy. Results The survival rates of 1a in biliary enteric drainage plus stereotactic radiotherapy group, pure stereotactic radiotherapy group and pure biliary enteric drainage group were 63%, 46.7%, respectively. Conclusion The treatment of advanced cholangiocarcinoma with choledoch-internal drainage combined with stereotactic radiotherapy is superior to that of simple stereotactic radiotherapy and cholangio-intestinal drainage