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住院号260,李×,女,15岁,山东平色县人,困 唇裂于88年1月18日入我科治疗。家族中有5个兄 姐因面裂畸形在出生后不久死亡。父母身体健康, 非近亲婚配,双方上三代直旁系中无类似畸形。李 母在1967年23岁时产部一胎,为健康女婴。李母在 妊娠后期因经常晕倒伴四肢抽搐,乡医按癫痫为其 治疗。李母在持续服苯妥英钠的同时,孕7产7, 6胎有面裂畸形,前5胎因不能哺乳生后死亡。患者 生于1973年,为单纯唇裂,可哺母乳,李母产后自 行停药。癫痫未再发作。1976年产第八胎,无畸 形,李母在1967~1976十年内共产8胎,详见附
Inpatient number 260, Li ×, female, 15 years old, Pingdingshan, Shandong, cleft lip cleft in January 18, 88 into my department for treatment. Five siblings of the family died of facial deformities shortly after birth. Parents healthy, non-relatives marriage, the two sides in the next three generations without any similar deformity. Li mother in 1967 23-year-old production department of a tire, a healthy baby girl. Li mother in the late pregnancy due to frequent fainting with extremities convulsions, township doctors for the treatment of epilepsy. Li continued to take phenytoin sodium at the same time, 7, 7, 7 births have cleavage deformities, the first 5 due to death after lactation. Born in 1973, the patient was a pure cleft lip, breastfeeding her mother, stopping her mother's delivery after she gave birth. Epilepsy no longer attacks. The eighth child born in 1976, no deformity, Lee mother in the 1967-1976 ten years of co-production of 8 tires, see attached