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1992年度我科共收治头颈部恶性肿瘤患者46例。门诊随机分为二组,放疗配合维生素A为综合组24例;不用维生素A为单放组22例。46例病人均用60CoT射线照射,总量为40~70GY/4~7周。综合组口服维生素A5万单位,每天三次,放疗结束时停用。经临床观察,病人在放疗中服用维生素A能降低皮肤、粘膜反应,既经济又方便。综合组皮肤反应I°14/23(60.86%),Ⅲ°3/23(13.04%)。单放组皮肤反应Ⅰ°5/23(21.73%),Ⅲ°11/23(47.82%)。综合组粘膜反应Ⅰ°17/23(73.91%),Ⅲ°2/23(8.69%)。单放组粘膜反应Ⅰ°3/23(13.04%),Ⅲ°11/23(47.82%)。综合组明显优于单放组,保证了放疗的顺利进行。
In 1992, our department received a total of 46 cases of head and neck cancer patients. Outpatients were randomly divided into two groups, radiotherapy with vitamin A for the comprehensive group of 24 cases; without vitamin A for the single release group of 22 cases. 46 patients were irradiated with 60CoT radiation, the total amount of 40 ~ 70GY / 4 ~ 7 weeks. Combined group of oral vitamin A5 unit, three times a day, the end of radiotherapy disabled. The clinical observation, the patient taking vitamin A in radiotherapy can reduce the skin, mucosal reactions, both economical and convenient. The combined group of skin reactions I ° 14/23 (60.86%), Ⅲ ° 3/23 (13.04%). The skin reactions of single group were Ⅰ ° 5/23 (21.73%) and Ⅲ ° 11/23 (47.82%). The combined group mucosal response Ⅰ ° 17/23 (73.91%), Ⅲ ° 2/23 (8.69%). Group mucosal response Ⅰ ° 3/23 (13.04%), Ⅲ ° 11/23 (47.82%). Comprehensive group was significantly better than the single group, to ensure the smooth progress of radiotherapy.