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实现纳米尺寸物体的合理设计与组装是纳米技术与精密工程的主要目标之一.DNA因其双链相互作用和螺旋几何构型的可预测性而使其成为构建纳米尺度结构的优秀建筑基元.DNA纳米结构在溶液状况改变时易分解.为提高DNA纳米结构的稳定性,一个链霉亲和素-生物素复合单元被引入到该纳米结构中.凝胶测试与熔点测试均证实链霉亲和素-生物素复合有助于提高DNA纳米结构的稳定性.该方法可广泛用于解决结构DNA纳米技术中的类似问题.
Achieving rational design and assembly of nanoscale objects is one of the major goals of nanotechnology and precision engineering because of their predictability of double-stranded interactions and helical geometry that make them excellent building blocks for building nanoscale structures .DNA nanostructures are susceptible to decomposition when the solution conditions change. To increase the stability of the DNA nanostructures, a streptavidin-biotin complex is introduced into the nanostructures. Both gel and melting point tests confirm that the Streptomyces Avidin-Biotin Complexes Help Improve the Stability of DNA Nanostructures This method can be widely used to solve similar problems in structured DNA nanotechnology.