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目的:研究卵巢浆液性交界性肿瘤的临床病理特点。方法:对该院2000年1月~2006年12月病理诊断为卵巢浆液性交界性肿瘤26例的治疗方法、病理特点、随访结果进行分析。结果:26例卵巢浆液性交界性肿瘤中,Ⅰ期18例,Ⅱ期6例,Ⅲ期2例。保守性手术治疗16例,根治性手术治疗10例。全部病例随访1~6年,保守性手术治疗的病例中,1例Ⅰ期患者于术后2年自然妊娠,孕38周剖宫产时发现肿瘤已恶变;2例Ⅱ期患者分别于术后半年、2年复发;根治性手术治疗10例未见复发。结论:卵巢浆液性交界性肿瘤预后较好,诊断仍然依靠显微镜下观察,手术是治疗的主要方式,化疗是否有益尚有争议,妊娠对肿瘤复发或恶变是否有影响有待进一步观察和研究,随访是发现肿瘤复发、提高生存率的重要手段。
Objective: To study the clinicopathological features of ovarian serous borderline tumors. Methods: The hospital from January 2000 to December 2006 pathological diagnosis of ovarian serous borderline tumors in 26 cases of treatment, pathological features, follow-up results were analyzed. Results: Twenty-six cases of ovarian serous borderline tumors included 18 cases of stage Ⅰ, 6 cases of stage Ⅱ and 2 cases of stage Ⅲ. Conservative surgery in 16 cases, radical surgery in 10 cases. All cases were followed up for 1 to 6 years. Among the cases of conservative surgery, 1 case of stage Ⅰ patients had natural pregnancy 2 years after cesarean section and 38 cases of cesarean section at the first trimester of pregnancy. Malignant tumors were found in 2 cases of stage Ⅱ after operation Six months, two years of recurrence; radical surgery in 10 cases no recurrence. Conclusion: The prognosis of ovarian serous borderline tumors is good. The diagnosis is still under the microscope. Surgery is the main way of treatment. Whether chemotherapy is beneficial or not remains controversial. Whether pregnancy has any effect on tumor recurrence or malignancy needs to be further observed and studied. The follow-up is Found tumor recurrence, an important means to improve the survival rate.