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目的调研我院人血白蛋白的使用情况,为完善医院人血白蛋白临床合理用药管理提供参考。方法取我院2013年应用人血白蛋白的住院患者病历,对患者年龄、科室分布、用量、用药理由、用药前血清白蛋白浓度等进行统计与分析,并与人血白蛋白说明书和美国大学医院联合会关于人血白蛋白的使用标准进行比较。结果我院15个临床科室涉及15类疾病使用人血白蛋白,用量较大的主要是肝胆疾病的患者;在个人用量分布方面,以使用30~40g的患者最多;用药理由以低蛋白血症所占比例最大,达51.66%;使用人血白蛋白前患者血清白蛋白分布主要集中在21~30g·L-1范围内。结论医院人血白蛋白的使用较广泛,且存在不合理使用的可能性,须加强人血白蛋白使用各环节的监管,提高合理用药水平。
Objective To investigate the use of human albumin in our hospital and provide a reference for improving the rational administration of human serum albumin in hospital. Methods The medical records of inpatients applying human serum albumin in our hospital from 2013 to 2013 were collected and analyzed in terms of patient’s age, department distribution, dosage, medication reason, serum albumin concentration before treatment, and human serum albumin manual and American University Hospital Federation for the use of human serum albumin standards for comparison. Results 15 clinical departments of our hospital were involved in the 15 kinds of diseases using human serum albumin, and the patients who mainly consumed hepatobiliary diseases were the most. In terms of the individual dosage distribution, the patients who used 30-40g were most used. The reason of the treatment was hypoproteinemia The largest proportion, up to 51.66%; before using serum albumin serum albumin distribution mainly concentrated in the range of 21 ~ 30g · L-1. Conclusion The use of human serum albumin in hospital is more extensive and there is a possibility of unreasonable use. It is necessary to strengthen the supervision of the use of human serum albumin and improve the rational use of drugs.