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目的探讨胃癌伴肝转移术后治疗的方法及其疗效。方法回顾性分析手术治疗的43例胃癌同时伴肝转移患者的临床资料。原发灶及转移灶同步切除19例(A组);对未切除的肝转移灶行局部治疗,24例行无水酒精瘤体内注射+门静脉栓塞化疗(B组)。其结果与同期收治条件类似的18例胃癌原发灶切除而肝转移灶未行治疗患者(C组)相比较。结果A组的1、3年生存率分别为57.9%、26.3%,B组1、3年生存率分别为50.0%、25.0%,组间差异无统计学意义(P>0.05);C组1、3年生存率分别为16.7%、0%,明显低于B组(P<0.05)。结论对胃癌肝转移灶无法切除患者应积极行肝转移灶的局部治疗,可明显改善患者预后。
Objective To investigate the treatment of gastric cancer with liver metastasis and its curative effect. Methods Retrospective analysis of surgical treatment of 43 cases of gastric cancer accompanied by liver metastases in patients with clinical data. Nineteen patients (group A) underwent primary resection of the primary tumor and metastasis. Local resection was performed on unresectable liver metastases and 24 patients received intravenous injection of portal vein chemoembolization (group B) with anhydrous alcoholic tumor. The results were compared with those of 18 patients with resected primary gastric cancer resected in the same period but not treated with metastatic liver metastases (Group C). Results The 1-year and 3-year survival rates in group A were 57.9% and 26.3%, respectively. The 1- and 3-year survival rates in group B were 50.0% and 25.0%, respectively. There was no significant difference between groups (P> 0.05) The 3-year survival rates were 16.7% and 0%, respectively, which were significantly lower than those in group B (P <0.05). Conclusion Local treatment of hepatic metastases should be actively performed on patients with unresectable liver metastases of gastric cancer, which can significantly improve the prognosis of patients.