即早基因c-fos作为神经功能活动的代谢性标志物,正常情况下,在中枢神经系统中可有基础水平的表达,而在神经细胞接受内外源刺激信号后,c-fos表达明显增加。近年来其与癫痫、脑血管病、脑外伤等神经系统疾病的关系研究越来越多,本文就近年来的研究进展综述如下。1即早基因c-fos概述在原癌基因家族中,有一类能被第二信使所诱 That early gene c-fos as a metabolic marker of neurological function, under normal circumstances, the central nervous system may have a basic level of expression, and in nerve cells to receive internal and external stimulation signals, c-fos expression was significantly increased. In recent years, there are more and more researches on the relationship between the neurological diseases such as epilepsy, cerebrovascular disease and traumatic brain injury. The research progress in recent years is summarized as follows. 1 immediate early gene c-fos Overview In the proto-oncogene family, there is a class can be induced by the second messenger